Computational Fluid Dynamics Analysis to Predict Endothelial Cells Migration during Flow Exposure Experiment with Placement of Two Stent Wires

Narendra Kurnia Putra, Zi Wang, Hitomi Anzai, Makoto Ohta

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

Stent deployment is currently used for many cardiovascular treatments. During its application, the presence of the stent inside the blood vessel will indeed cause some change in both flow environment and also vessel wall's cellular conditions. This research intends to learn about the flow phenomenon of how vessel wall endothelial cells (ECs) react to the presence of stent wires within a microfluidic flow chamber environment. Computational fluid dynamics (CFD) simulation analysis of the microfluidic flow chamber system has been performed for observing the hemodynamics phenomena in the chamber. Moreover, CFD method also can be beneficial as a planning step for a successful experimental study. We found that under the two wires configurations, high wall shear stress (WSS) area is developed on the downstream side of the wires. Based on the analysis of WSS and WSS gradients (WSSG) conditions, ECs morphological change and migration are likely to occur some specific area.

本文言語English
ホスト出版物のタイトル40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
出版社Institute of Electrical and Electronics Engineers Inc.
ページ5454-5457
ページ数4
ISBN(電子版)9781538636466
DOI
出版ステータスPublished - 2018 10 26
イベント40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 - Honolulu, United States
継続期間: 2018 7 182018 7 21

出版物シリーズ

名前Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
2018-July
ISSN(印刷版)1557-170X

Other

Other40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
国/地域United States
CityHonolulu
Period18/7/1818/7/21

ASJC Scopus subject areas

  • 信号処理
  • 生体医工学
  • コンピュータ ビジョンおよびパターン認識
  • 健康情報学

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