Complete separation of ternary mixture of amino acids using continuous rotating annular chromatography with partial recycling of effluent

Takuya Fukumura, Vinay M. Bhandari, Akio Kitakawa, Toshikuni Yonemoto

研究成果: Article査読

5 被引用数 (Scopus)

抄録

Continuous rotating annular chromatography with partial recycling of the effluent (CRAC-PRE) was used for the separation of a ternary mixture of amino acids. A mathematical model describing the separation process was constructed to find the optimized operating conditions. The effectiveness of the CRAC-PRE for the separation of a ternary mixture was experimentally and theoretically elucidated by comparison to conventional CRAC. A recycling loop which gives reasonable separation was successfully arranged on the basis of the numerical simulation result. A combination of CRAC-PRE with the step elution method was applied to the complete separation of a ternary mixture of amino acids.

本文言語English
ページ(範囲)778-784
ページ数7
ジャーナルJOURNAL of CHEMICAL ENGINEERING of JAPAN
33
5
DOI
出版ステータスPublished - 2000

ASJC Scopus subject areas

  • 化学 (全般)
  • 化学工学(全般)

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