Complete amino-acid sequence of the β-subunit of VTX from venom of the stonefish (Synanceia verrucosa) as identified from cDNA cloning experiments

Pascale Garnier, Frédéric Ducancel, Tomohisa Ogawa, Jean Claude Boulain, Françoise Goudey-Perrière, Claude Perrière, André Ménez

研究成果: Article査読

20 被引用数 (Scopus)

抄録

A cDNA encoding a subunit of the verrucotoxin (VTX) has been identified from a cDNA library derived from stonefish venom glands. It encodes a polypeptide of 708 amino-acid residues, followed by a 3'-untranslated region of 895 bp long. The ORF contains the complete mature sequence of the β-subunit of the VTX, as inferred from both the presence of an identical N-terminus sequence and 96% homology among the 506 amino terminus residues found in the partial sequence of the β-subunit of the stonustoxin from Synanceia horrida (Ghadessy, F.J., Jeyaseelan, K., Chung, M.C.M., Khoo, H.E. and Yuen, R. (1994) Toxicon 32, 1684-1688). Upstream the mature sequence, we noticed the presence of an incomplete peptide of a 13 amino acids, whose unusual primary structure supports the idea of the existence of a propeptide and/or of a new secretion signal.

本文言語English
ページ(範囲)1-5
ページ数5
ジャーナルBiochimica et Biophysica Acta - Protein Structure and Molecular Enzymology
1337
1
DOI
出版ステータスPublished - 1997 1 4
外部発表はい

ASJC Scopus subject areas

  • 生物理学
  • 構造生物学
  • 生化学
  • 分子生物学

フィンガープリント

「Complete amino-acid sequence of the β-subunit of VTX from venom of the stonefish (Synanceia verrucosa) as identified from cDNA cloning experiments」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル