Comparison of Cardiopulmonary Effects of Medetomidine-Midazolam, Acepromazine-Butorphanol and Midazolam-Butorphanol in Dogs

K. Kojima, R. Nishimura, T. Mutoh, K. Takao, S. Matsunaga, M. Mochizuki, N. Sasaki

研究成果: Article査読

18 被引用数 (Scopus)

抄録

Cardiopulmonary effects of intramuscualar administration of medetomidine-midazolam at 20 μg/kg and 0.3 mg/kg, respectively (MM), acepromazine-butorphanol at 0.05 and 0.2 mg/kg, respectively (AB), and midazolam-butorphanol at 0.1 and 0.2 mg/kg, respectively (MB), were compared in dogs. MM produced relatively large cardiovascular changes such as bradycardia, hypertension, a decrease in cardiac output and vasoconstriction. AB produced moderate cardiovascular changes. Hypotension was observed within 5 min after administration and the mean arterial blood pressure decreased by 30 % at 20 min after administration. MB produced decreases in arterial blood pressure and cardiac output, but these changes were small and, of the combinations evaluated in this study, MB had the mildest cardiovascular effects.

本文言語English
ページ(範囲)353-359
ページ数7
ジャーナルJournal of Veterinary Medicine Series A: Physiology Pathology Clinical Medicine
46
6
DOI
出版ステータスPublished - 1999 8
外部発表はい

ASJC Scopus subject areas

  • 病理学および法医学
  • 獣医学(全般)

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