Comparison of adjuvant chemotherapy and radiotherapy in patients with cervical adenocarcinoma of the uterus after radical hysterectomy: SGSG/TGCU Intergroup surveillance

M. Shimada, R. Nishimura, M. Hatae, M. Hiura, K. Takehara, T. Tase, H. Yamada, H. Kurachi, T. Sugiyama, J. Kigawa

研究成果: Article査読

11 被引用数 (Scopus)

抄録

Purpose: The authors conducted this retrospective study to evaluate the efficacy of radiotherapy (RT) for high-risk patients with adenocarcinoma (AC) compared with chemotherapy (CT) after radical hysterectomy. Materials and Methods: There were 263 patients with AC and 58 with adenosquamous cell carcinoma (ASCC). Of these 321 patients, 151 received adjuvant treatment. Of these 151 patients, 69 received radiotherapy (RT) alone, including concurrent chemoradiotherapy (CCRT) with weekly cisdiamminedichloroplatinum (CDDP), 64 patients received CT alone, and 18 patients received concomitant RT and CT (RT + CT). Results: The five-year overall survival (OS) was 70.9% for patients receiving RT, 79.2% for CT, and 66.2% for RT + CT. Adjuvant treatment did not affect the incidence or the pattern of recurrence. The incidence of lymph node involvement was 9.0% in Stage Ib1, 23.9% in Stage Ib2, 30.8% in Stage IIa, and 41.2% in Stage IIb. Conclusions: Adjuvant CT may be effective for high-risk patients with cervical adenocarcinoma.

本文言語English
ページ(範囲)425-428
ページ数4
ジャーナルEuropean Journal of Gynaecological Oncology
34
5
出版ステータスPublished - 2013
外部発表はい

ASJC Scopus subject areas

  • 腫瘍学
  • 産婦人科学

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