Combined therapy with hypothermia and anticytokine agents in influenza A encephalopathy

Mitsutoshi Munakata, Rie Kato, Hiroyuki Yokoyama, Kazuhiro Haginoya, Yoshiko Tanaka, Jun Kayaba, Taku Kato, Reiko Takayanagi, Hiroko Endo, Ryuiti Hasegawa, Yutaka Ejima, Kunihiko Hoshi, Kazuie Iinuma

研究成果: Article査読

68 被引用数 (Scopus)

抄録

Two children with influenza A-related encephalopathy were treated with a combination of mild hypothermia (deep body temperature of the forehead: 35°C) and anticytokine agents (high-dose methylprednisolone and ulinastatin), while receiving amantadine. One of the cases exhibited acute necrotizing encephalopathy on computed tomography (CT). Although no severe complications occurred, correctable hypokalemia and hyperglycemia occurred in both cases. Both patients recovered without any neurological sequelae. Our therapeutic protocol appears to be effective for managing influenza A-related encephalopathy. (C) 2000 Elsevier Science B.V.

本文言語English
ページ(範囲)373-377
ページ数5
ジャーナルBrain and Development
22
6
DOI
出版ステータスPublished - 2000 10 30

ASJC Scopus subject areas

  • 小児科学、周産期医学および子どもの健康
  • 発達神経科学
  • 臨床神経学

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