Combined therapy after superselective arterial cisplatin infusion to treat maxillary squamous cell carcinoma

Kiyoto Shiga, Junkichi Yokoyama, Sho Hashimoto, Shigeru Saijo, Masaru Tateda, Takenori Ogawa, Mika Watanabe, Toshimitsu Kobayashi

研究成果: Article

37 引用 (Scopus)

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Objective: We sought to assess the efficacy of combined therapy after superselective arterial cisplatin infusion (SACI) therapy to treat the maxillary squamous cell carcinoma. Study Design: We conducted a retrospective chart review of 50 patients. After completion of two courses of SACI, 25 of the patients were successively treated by concurrent SACI and radiotherapy (AR), while the other 25 patients were treated by surgery with postoperative radiotherapy (ASR). Results: Patients with surgery (ASR) had an 88% local control rate with 75% disease-free survival rate at 60 months by Kaplan-Meier analysis, compared with 62% disease-free survival rate for patients with AR treatment. A particularly good outcome was obtained in T4 cases of the ASR group (n = 8) whose 5-year survival rate was 87% and local control rate was 100%. Conclusion/Significance: Combined SACI therapy is very effective for the treatment of maxillary squamous cell carcinomas and contributes to the improving prognoses of patients and organ preservation rates.

元の言語English
ページ(範囲)1003-1009
ページ数7
ジャーナルOtolaryngology - Head and Neck Surgery
136
発行部数6
DOI
出版物ステータスPublished - 2007 6 1

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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