Cobalt-catalyzed addition of arylzinc reagents to norbornene derivatives through 1,4-cobalt migration

Boon Hong Tan, Naohiko Yoshikai

研究成果: Article査読

34 被引用数 (Scopus)

抄録

A cobalt-diphosphine catalyst promotes the addition of an arylzinc reagent to a norbornene derivative to afford o-(2-exo-norbornyl)arylzinc species. This "migratory arylzincation" reaction is considered to involve insertion of norbornene into an arylcobalt species, alkyl-to-aryl 1,4-cobalt migration, and transmetalation between the resulting o-(2-exo-norbornyl)arylcobalt species and the arylzinc reagent. The o-(2-exo-norbornyl)arylzinc species can be intercepted by common organic electrophiles under copper or palladium catalysis.

本文言語English
ページ(範囲)3392-3395
ページ数4
ジャーナルOrganic letters
16
12
DOI
出版ステータスPublished - 2014 6月 20
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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