TY - JOUR
T1 - Close encounters with apolipoprotein E receptors
AU - Yamamoto, Tokuo
AU - Bujo, Hideaki
PY - 1996/1/1
Y1 - 1996/1/1
N2 - Most of the LDL receptor family members recognize apolipoprotein E. The structures of the VLDL receptor, and recently identified apolipoprotein E receptor 2, closely resemble the LDL receptor. Recent studies have demonstrated that the VLDL receptor is responsible for the reproduction of premammalian species by mediating oogenesis. Despite the importance of the VLDL receptor in premammalian species, the biological role of the mammalian VLDL receptor is still unclear. Apolipoprotein E receptor 2 is structurally most closely related to the LDL receptor and expressed predominantly in brain. This newly identified receptor may play a role in the uptake of cholesterol in the central nervous system.
AB - Most of the LDL receptor family members recognize apolipoprotein E. The structures of the VLDL receptor, and recently identified apolipoprotein E receptor 2, closely resemble the LDL receptor. Recent studies have demonstrated that the VLDL receptor is responsible for the reproduction of premammalian species by mediating oogenesis. Despite the importance of the VLDL receptor in premammalian species, the biological role of the mammalian VLDL receptor is still unclear. Apolipoprotein E receptor 2 is structurally most closely related to the LDL receptor and expressed predominantly in brain. This newly identified receptor may play a role in the uptake of cholesterol in the central nervous system.
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U2 - 10.1097/00041433-199610000-00007
DO - 10.1097/00041433-199610000-00007
M3 - Short survey
C2 - 8937520
AN - SCOPUS:0029807484
SN - 0957-9672
VL - 7
SP - 298
EP - 302
JO - Current Opinion in Lipidology
JF - Current Opinion in Lipidology
IS - 5
ER -
