Clinical characteristics of patients with spontaneous remission of variant angina

Hideki Tashiro, Hiroaki Shimokawa, Samon Koyanagi, Akira Takeshita

研究成果: Article査読

12 被引用数 (Scopus)

抄録

To determine the factors influencing the spontaneous remission of variant angina, clinical characteristics were examined in 75 Japanese patients with variant angina. Spontaneous remission was defined as an absence of angina at rest for at least 3 months after withdrawal of treatment with calcium antagonists. This remission occurred in 12 patients (16%) (remission group), while angina persisted despite treatment with calcium antagonists and nitrates in 33 patients (44%) (persistent angina group). The remaining 30 patients (40%) were angina-free under treatment with calcium antagonists and/or nitrates (angina-free on treatment group). The prevalence of significant coronary artery stenosis (>75%) was significantly higher in the remission group than in the persistent angina group (44% vs 7%, p<0.05). The prevalence of cessation of smoking was significantly higher in the remission group than in the persistent angina group (92% vs 39%, p<0.01). Age, gender, other coronary risk factors, disease activity of variant angina and site of myocardial ischemia during anginal attacks were not statistically different among the 3 groups. There data indicate that remission of variant angina occurs more frequently in patients with than in those without significant coronary artery stenosis and that cessation of smoking is an important factor for remission of variant angina.

本文言語English
ページ(範囲)117-122
ページ数6
ジャーナルJAPANESE CIRCULATION JOURNAL
57
2
DOI
出版ステータスPublished - 1993
外部発表はい

ASJC Scopus subject areas

  • 生理学
  • 循環器および心血管医学

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