Clinical application of18F-FUdR in glioma patients - PET study of nucleic acid metabolism

Motonobu Kameyama, Kiichi Ishiwata, Yuji Tsurumi, Jun Itoh, Kiyotaka Sato, Ryuichi Katakura, Takashi Yoshimoto, Jun Hatazawa, Masatoshi Ito, Tatsuo Ido

研究成果: Article査読

13 被引用数 (Scopus)

抄録

Positron emission tomography was used to investigate the metabolism of nucleic acids by18F-fluoro-2′-deoxyuridine (18F-FUdR) in 22 patients with gliomas. Sixteen cases of high grade glioma clearly demonstrated a region of high activity with a differential absorption rate (DAR) of 0.64 ± 0.34. Six cases of low grade glioma failed to reveal a positive image of the tumor and the DAR in tumor was 0.21 ± 0.042 (p < 0.01). This PET-18F-FUdR study succeeded in differentiating high and low grade gliomas from the view point of nucleic acid metabolism.

本文言語English
ページ(範囲)53-61
ページ数9
ジャーナルJournal of Neuro-Oncology
23
1
DOI
出版ステータスPublished - 1995 2

ASJC Scopus subject areas

  • 腫瘍学
  • 神経学
  • 臨床神経学
  • 癌研究

フィンガープリント

「Clinical application of<sup>18</sup>F-FUdR in glioma patients - PET study of nucleic acid metabolism」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル