Chemistry of puffer fish toxin

研究成果: Review article査読

75 被引用数 (Scopus)

抄録

Tetrodotoxin (TTX) is well known as the puffer fish toxin. Naturally occurring analogs of TTX have been isolated from puffer fish, newts and frogs, and their structures have been determined by spectroscopic methods. Additionally, TTX analogs have been prepared by chemical modification to investigate its binding site on sodium channels and the structure-activity relationship of TTX. In this article, the NMR data of TTX analogs are listed, and the chemical modification methods for preparation of TTX probes are summarized.

本文言語English
ページ(範囲)51-66
ページ数16
ジャーナルJournal of Toxicology - Toxin Reviews
20
1
DOI
出版ステータスPublished - 2001

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

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