TY - JOUR
T1 - Chemical reduction of Ag+to Ag employing organic electron donors
T2 - evaluation of the effect of Ag+-mediated cytosine-cytosine base pairing on the aggregation of Ag nanoparticles
AU - Dairaku, Takenori
AU - Kawai, Rika
AU - Nozawa-Kumada, Kanako
AU - Yoshida, Kentaro
AU - Ono, Tetsuya
AU - Kondo, Yoshinori
AU - Kondo, Jiro
AU - Ono, Akira
AU - Tanaka, Yoshiyuki
AU - Kashiwagi, Yoshitomo
N1 - Funding Information:
This work was supported by JSPS KAKENHI (Grant No. 20K14597 and 21H01956 to T.D. and A.O., respectively) and the Foundation for Ohu University Joint Research Fund. We thank Quantum Design Japan, Inc. for conducting the NTA measurements with NanoSight.
Publisher Copyright:
© The Royal Society of Chemistry 2021.
PY - 2021/9/21
Y1 - 2021/9/21
N2 - Ag+-mediated base pairing is valuable for synthesising DNA-based silver nanoparticles (AgNPs) and nanoclusters (AgNCs). Recently, we reported the formation of a [Ag(cytidine)2]+complex in dimethyl sulfoxide (DMSO), which facilitated the evaluation of the effect of cytosine-Ag+-cytosine (C-Ag+-C) base pairing on the degree of AgNP aggregation in solution. As an aprotic solvent, DMSO was expected to dissolve the [Ag(cytidine)2]+complex, and powerful reducing agents, such as organic electron donors. In this study, the chemical reduction of a cytidine/Ag+system using a powerful reducing agent tetrakis(dimethylamino)ethylene (TDAE) was investigated.1H/13C/15N NMR spectroscopic evidence was obtained to identify the iminium dication (TDAE2+), which is an oxidised form of TDAE. The results were compared with those obtained using another organic electron donor, tetrathiafulvalene (TTF), which exhibits a relatively lower reduction activity than TDAE. AgNPs preparedviaredox reaction between [Ag(cytidine)2]+and organic electron donors (TDAE and TTF) were characterised using UV-Vis spectroscopy and nanoparticle tracking analysis. It was found that the formation of C-Ag+-C base pairing inhibited the aggregation of AgNPs in solution. In addition, in the presence of cytidine, the total concentration of the AgNP solution was affected by the reduction activity of the reducing agent.
AB - Ag+-mediated base pairing is valuable for synthesising DNA-based silver nanoparticles (AgNPs) and nanoclusters (AgNCs). Recently, we reported the formation of a [Ag(cytidine)2]+complex in dimethyl sulfoxide (DMSO), which facilitated the evaluation of the effect of cytosine-Ag+-cytosine (C-Ag+-C) base pairing on the degree of AgNP aggregation in solution. As an aprotic solvent, DMSO was expected to dissolve the [Ag(cytidine)2]+complex, and powerful reducing agents, such as organic electron donors. In this study, the chemical reduction of a cytidine/Ag+system using a powerful reducing agent tetrakis(dimethylamino)ethylene (TDAE) was investigated.1H/13C/15N NMR spectroscopic evidence was obtained to identify the iminium dication (TDAE2+), which is an oxidised form of TDAE. The results were compared with those obtained using another organic electron donor, tetrathiafulvalene (TTF), which exhibits a relatively lower reduction activity than TDAE. AgNPs preparedviaredox reaction between [Ag(cytidine)2]+and organic electron donors (TDAE and TTF) were characterised using UV-Vis spectroscopy and nanoparticle tracking analysis. It was found that the formation of C-Ag+-C base pairing inhibited the aggregation of AgNPs in solution. In addition, in the presence of cytidine, the total concentration of the AgNP solution was affected by the reduction activity of the reducing agent.
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U2 - 10.1039/d1dt01927a
DO - 10.1039/d1dt01927a
M3 - Article
AN - SCOPUS:85114914840
VL - 50
SP - 12208
EP - 12214
JO - Dalton Transactions
JF - Dalton Transactions
SN - 1477-9226
IS - 35
ER -