Chemical characterization of milk oligosaccharides of the brown bear, Ursus arctos yesoensis

Tadasu Urashima, Yohko Kusaka, Tadashi Nakamura, Tadao Saito, Naoko Maeda, Michael Messer

    研究成果: Article査読

    39 被引用数 (Scopus)

    抄録

    Two tri-, two hexa- and two deca-saccharides were isolated from bear milk by chloroform/methanol extraction and gel filtration. The oligosaccharides were characterized, mainly by 1H-NMR, as follows: Gal α 1-3Gal β 1-4Glc (α 3'-galactosyllactose); Fuc α 1-2Gal β 1-4Glc (2'-fucosyllactose); Gal α 1-3Gal β 1-4[Fuc α 1-3]GlcNAc β 1-3Gal β 1-4Glc (monofucosylhexasaccharide); Fuc α 1-2Gal β 1-4[Fuc α 1-3]GlcNAc β 1-3Gal β 1-4Glc (difucosylhexasaccharide); Gal α 1-3Gal β 1-4[Fuc α 1-3]GlcNAc β 1 (6) (Gal β 1-4Glc (difucosyldecasaccharide) Gal α 1-3Gal β 1-4[Fuc α 1-3]GlcNAc β 1 (3); Fuc α 1-2Gal β 1-4[Fuc α 1-3]GlcNAc β 1 (6) (Gal β 1-4Glc (tetrafucosyldecasaccharide)) (3) Fuc α 1-2Gal β 1-4[Fuc α 1-3]GlcNAc β 1. Both trisaccharides were present in bear milk at a higher concentration than lactose.

    本文言語English
    ページ(範囲)247-255
    ページ数9
    ジャーナルBiochimica et Biophysica Acta - General Subjects
    1334
    2-3
    DOI
    出版ステータスPublished - 1997 3月 15

    ASJC Scopus subject areas

    • 生物理学
    • 生化学
    • 分子生物学

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