Chemical characterisation of six oligosaccharides in a sample of colostrum of the brown capuchin, Cebus apella (Cebidae: Primates)

Tadasu Urashima, Yuhko Kawai, Tadashi Nakamura, Ikichi Arai, Tadao Saito, Misako Namiki, Koh ichi Yamaoka, Kazuyuki Kawahawa, Michael Messer

研究成果: Article査読

33 被引用数 (Scopus)

抄録

Carbohydrates were extracted from a sample of brown capuchin colostrum and six of the component oligosaccharides were separated and purified by gel filtration and preparative thin layer chromatography. Their structures were determined by 1H-NMR to be as follows: Gal β 1→4[Fuc α 1→3]Glc (3- fucosyllactose) Gal β 1→3Gal β 1→4Glc (β-3'-galactosyllactose) Gal β 1→6Gal β 1→4Glc (β-6'-galactosyllactose) Gal β 1→3[Gal β 1→4GlcNAc β 1→6]Gal β 1→4Glc (lacto-N-novopentaose I) Gal β 1→4GlcNAc β 1→3[Gal β 1→4GlcNAc β 1→6]Gal β 1→4Glc (lacto-N-neohexaose) Neu5Ac α 2→3Gal β 1→4Glc (3'-N-acetylneuraminyllactose) Of these, all except lacto-N- novopentaose I have been previously found in human milk or colostrum.

本文言語English
ページ(範囲)295-300
ページ数6
ジャーナルComparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology
124
3
DOI
出版ステータスPublished - 1999 11

ASJC Scopus subject areas

  • 免疫学
  • 薬理学

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