Characterization of STRO-1 positive cells derived from human wisdom tooth germs

Yoko Kobayashi, Daisuke Nishihara, Naoki Endo, Koji Kindaichi, Junko Kindaichi, Masashi Komatsu

研究成果: Chapter

抄録

Recently, the research on the stem cells is developing rapidly in the odontology. Mesenchymal stem cells (MSCs) have the possibility useful for the stem cell treatment and the tissue engineering. STRO-1 is one of the mesenchymal stem cell markers. In this study, we examined the characterization of STRO-1 posi- tive cells derived from human wisdom tooth germs (hWTGs) compared with STRO-1 negative cells. As positive control, we used human mesenchymal stem cells (HMSC) on purchase. STRO-1 positive cells derived from hWTGs showed Alcian blue positive matrix like HMSC when cultured in chondrogenic induction medium. STRO-1 negative cells from hWTGs did not show such matrix. Nodule formation stained with Alizarin red was performed not only by STRO-1 positive cells but also STRO-1 negative cells cultured in osteogenic induction medium. It is suggested that STRO-1 positive cells derived from hWTGs are useful for the stem cell treatment and the tissue engineering.

本文言語English
ホスト出版物のタイトルInterface Oral Health Science 2011
出版社Springer Japan
ページ119-121
ページ数3
ISBN(電子版)9784431540700
ISBN(印刷版)9784431540694
DOI
出版ステータスPublished - 2012 1 1

ASJC Scopus subject areas

  • 歯科学(全般)

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