Characterization of Monoclonal Antibodies against Human Parvovirus B19

Nobuo Yaegashi, Kohtaro Tada, Kinnya Nagata, Kazuo Sugamura

研究成果: Article査読

26 被引用数 (Scopus)

抄録

Eleven hybridoma cell lines producing mouse monoclonal antibodies (mAbs) against human parvovirus B19 were established. Their specificity was as follows. Approximately 5% of fetal erythroid cells inoculated with B19 reacted with all the mAbs and with anti-B19 positive human serum, but not with negative serum by indirect double immunofluorescence staining. All the mAbs recognized both VP-1 (84 kDa) and VP-2 (58 kDa) capsid proteins of B19 virions propagated in vitro and in vivo by Western blotting, and immunoprecipitated B19 virions.

本文言語English
ページ(範囲)561-567
ページ数7
ジャーナルMICROBIOLOGY and IMMUNOLOGY
33
7
DOI
出版ステータスPublished - 1989

ASJC Scopus subject areas

  • 微生物学
  • 免疫学
  • ウイルス学

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