CGRP in peripherally axotomized mesencephalic trigeminal neurones of the rat

Akihiro Yoshida, Hiroyuki Ichikawa, Tomosada Sugimoto

研究成果: Article査読

13 被引用数 (Scopus)

抄録

Immunoreactivities for substance P (SP-ir) and calcitonin gene-related peptide (CGRP-ir) were examined in neurones in the mesencephalic trigeminal tract nucleus of nerve-injured rats. One week following unilateral transection of the trigeminal root, the masseteric nerve (MN) or the inferior alveolar nerve (IAN), CGRP-ir but not SP-ir was detected in these neurones bilaterally with ipsilateral dominance. Most of the CGRP-ir (immunoreactive) neurones were retrogradely labelled when fluorogold (FG) had been applied to the proximal stump of the MN or the IAN. Sham surgery including insult to the masseter muscle induced CGRP-ir while skin incision did not.

本文言語English
ページ(範囲)837-840
ページ数4
ジャーナルNeuroReport
6
6
DOI
出版ステータスPublished - 1995 4月
外部発表はい

ASJC Scopus subject areas

  • 神経科学(全般)

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