cDNA cloning and expression of human lactosylceramide synthase

Minoru Takizawa, Tomoko Nomura, Etsuji Wakisaka, Naonobu Yoshizuka, Junken Aoki, Hiroyuki Arai, Keizo Inoue, Michihiro Hattori, Noboru Matsuo

研究成果: Article査読

26 被引用数 (Scopus)

抄録

Lactosylceramide synthase is an enzyme that catalyzes the transfer of galactose from UDP-Gal to glucosylceramide, and thus participates in the biosynthesis of most glycolipids in mammals. We have isolated and sequenced the cDNA clone encoding human lactosylceramide synthase. The deduced amino acid sequence of the human lactosylceramide synthase showed 94.2% identity with rat lactosylceramide synthase. Northern blotting analysis revealed that lactosylceramide synthase mRNA was expressed in various tissues, with the highest level in brain and adrenal gland. Copyright (C) 1999.

本文言語English
ページ(範囲)301-304
ページ数4
ジャーナルBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
1438
2
DOI
出版ステータスPublished - 1999 5 18
外部発表はい

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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