Caspase signaling in animal development

研究成果: Review article査読

59 被引用数 (Scopus)

抄録

The caspases are a family of cysteine proteases that function as central regulators of cell death. Recent investigations in Caenorhabditis elegans, Drosophila, and mice indicate that caspases are essential not only in controlling the number of cells involved in sculpting or deleting structures in developing animals, but also in dynamic cell processes such as cell-fate determination, compensatory proliferation of neighboring cells, and actin cytoskeleton reorganization, in a non-apoptotic context during development. This review focuses primarily on caspase functions involving their enzymatic activity.

本文言語English
ページ(範囲)137-148
ページ数12
ジャーナルDevelopment Growth and Differentiation
53
2
DOI
出版ステータスPublished - 2011 2
外部発表はい

ASJC Scopus subject areas

  • 発生生物学
  • 細胞生物学

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