Cardiac-related sympathetic nerve activity during circulation with only the left ventricular assist device

Tomoyuki Yambe, S. Nitta, Y. Katahira, T. Sonobe, S. Naganuma, H. Akiho, S. Chiba, Y. Kakinuma, H. Hayashi, K. Izutsu, Y. Kikuchi, T. Naganuma, S. Sugawara, M. Tanaka, M. Miura, N. Sato, H. Mohri, Makoto Yoshizawa, H. Takeda

研究成果: Article査読

4 被引用数 (Scopus)

抄録

Circulatory maintenance with a left ventricular assist device (LVAD) alone during cardiac arrest until heart transplantation has been evaluated. To assess the effect on the autonomic nervous system, the sympathetic neurogram was analyzed by power spectrum and coherence function. LVAD were inserted between the left atrium and the descending aorta in seven adult mongrel dogs and ventricular fibrillation was induced electrically. Renal sympathetic nerve activity (RSNA) was detected by bipolar electrodes attached to the left renal sympathetic nerve. Values of squared coherence between the arterial pulse wave and RSNA were calculated. Under the condition of circulatory maintenance with only LVAD, coherence at the cardiac rhythm frequency was decreased, and coherence at the LVAD pumping rhythm frequency was increased. These results indicate that the arterial pulse wave observed during maintenance of the circulation with only LVAD contributed to the sympathetic neurogram.

本文言語English
ページ(範囲)49-54
ページ数6
ジャーナルInternational Journal of Artificial Organs
15
1
出版ステータスPublished - 1992 1 1

ASJC Scopus subject areas

  • バイオエンジニアリング
  • 医学(その他)
  • 生体材料
  • 生体医工学

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