Capacitance extraction method for a free-standing bilayer lipid membrane formed over an aperture in a nanofabricated silicon chip

Yasutaka Tomioka, Shogo Takashima, Masataka Moriya, Hiroshi Shimada, Fumihiko Hirose, Ayumi Hirano-Iwata, Yoshinao Mizugaki

研究成果: Article査読

抄録

A bilayer lipid membrane (BLM) is the main component of the cell membrane of living organisms, which can be formed artificially. Although the specific capacitance of a BLM is known to be in the range of 0.4-1.0 μF cm-2, many previous works that formed free-standing BLMs over an aperture in silicon chips reported larger values beyond this typical range, which suggests that equivalent-circuit models are not adequate. In this work, we modified the equivalent-circuit model by adding a resistance element of silicon. To evaluate the validity of the modified model, we applied the model to the results of electrochemical impedance spectroscopy for free-standing BLMs formed over an aperture in nanofabricated silicon chips. The derived specific capacitance values were 0.57 ± 0.08 μF cm-2, which settles in the typical range.

本文言語English
論文番号SIIK02
ジャーナルJapanese journal of applied physics
59
DOI
出版ステータスPublished - 2020 6 1

ASJC Scopus subject areas

  • 工学(全般)
  • 物理学および天文学(全般)

フィンガープリント

「Capacitance extraction method for a free-standing bilayer lipid membrane formed over an aperture in a nanofabricated silicon chip」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル