Bone induction by controlled release of BMP-2 from a biodegradable hydrogel in various animal species -from mouse to non-human primate

Masaya Yamamoto, Yoshitake Takahashi, Yasuhiko Tabata

研究成果: Article査読

3 被引用数 (Scopus)

抄録

The objective of this study is to examine feasibility of biodegradable gelatin hydrogels incorporating bone morphogenetic protein (BMP)-2 in inducing bone regeneration at a bone defect of non-human primates and rabbits considering their BMP-2 release profiles. As a result, controlled release by the hydrogel system enabled BMP-2 to induce successful bone regeneration in non-human primates even at the BMP-2 dose as low as that for rabbit case (0.034 mg of BMP-2/cm3 of hydrogel).

本文言語English
ページ(範囲)253-256
ページ数4
ジャーナルKey Engineering Materials
288-289
DOI
出版ステータスPublished - 2005
外部発表はい

ASJC Scopus subject areas

  • 材料科学(全般)
  • 材料力学
  • 機械工学

フィンガープリント

「Bone induction by controlled release of BMP-2 from a biodegradable hydrogel in various animal species -from mouse to non-human primate」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル