Biological significance of HCV in various kinds of lymphoid cells

Yasuteru Kondo, Yoshiyuki Ueno, Tooru Shimosegawa

研究成果: Review article査読

7 被引用数 (Scopus)

抄録

It has been reported that HCV can infect not only hepatocytes but also various kinds of lymphoid cells. Although many reports have described the biological significance of lymphotropic HCV, the issue remains controversial since the target lymphoid cells might have various kinds of functions in the immune system. One of the important roles of lymphoid cells in HCV replication is being a reservoir of HCV. Several groups described the detection of HCV-RNA in lymphoid cells after HCV eradication in plasma. Another important role of lymphotropic HCV is that it acts as a carcinogenic agent and induces immune dysfunction. In this paper, we summarize the reports regarding the biological significance of lymphotropic HCV in representative lymphoid cells.

本文言語English
論文番号647581
ジャーナルInternational Journal of Microbiology
DOI
出版ステータスPublished - 2012

ASJC Scopus subject areas

  • 微生物学
  • 微生物学(医療)

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