Biofabrication Using Electrochemical Devices and Systems

Kosuke Ino, Fumisato Ozawa, Ning Dang, Kaoru Hiramoto, Shodai Hino, Rise Akasaka, Yuji Nashimoto, Hitoshi Shiku

研究成果: Article査読

5 被引用数 (Scopus)

抄録

Biofabrication is roughly defined as techniques producing complex 2D and 3D tissues and organs from raw materials such as living cells, matrices, biomaterials, and molecules. It is useful for tissue engineering, regenerative medicine, drug screening, and organs-on-a-chip. Biofabrication could be carried out by microfluidic techniques, optical methods, microfabrication, 3D bioprinting, etc. Meanwhile, electrochemical devices and/or systems have also been reported. In this progress report, the recent advances in applying these devices/systems for biofabrication are summarized. After introducing the concept of biofabrication, biofabrication strategies using electrochemical approaches are summarized. Then, various electrochemical systems such as probes and chip devices are described. Next, the biofabrication of hydrogels for 3D cell culture, electrochemical modification on cell culture surfaces, electrodeposition of conductive materials in hydrogels for cell culture, and biofabrication of cell aggregates using dielectrophoresis is discussed. In addition, electrochemical stimulation methods such as electrotaxis are mentioned as promising techniques for biofabrication. Finally, future research directions in this field and the application prospects are highlighted.

本文言語English
論文番号1900234
ジャーナルAdvanced Biosystems
4
4
DOI
出版ステータスPublished - 2020 4 1

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Biochemistry, Genetics and Molecular Biology(all)

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