Bile acid and colorectal cancer

研究成果: Chapter

1 被引用数 (Scopus)

抄録

Colorectal cancer is one of the most common causes of cancer death worldwide. The mechanism of colorectal carcinogenesis is still unknown, so that the prevention of colorectal cancer is strongly desired. The bile acids, cholesterol derivatives, were thought to be implicated in the pathogenesis of many diseases. In particular, secondary bile acids are thought to be associated with the colorectal carcinogenesis regarding the colorectal mucosal proliferation, apoptosis, and oxidative DNA damage. On the other hand, certain bile acids, ursodeoxycholate, might protect against colorectal carcinogenesis. This review will examine the opposing effects on colorectal tumor promotion and tumor inhibition.

本文言語English
ホスト出版物のタイトルBile Acids in Gastroenterology
ホスト出版物のサブタイトルBasic and Clinical
出版社Springer Japan
ページ185-192
ページ数8
ISBN(電子版)9784431560623
ISBN(印刷版)9784431560609
DOI
出版ステータスPublished - 2017 4 3
外部発表はい

ASJC Scopus subject areas

  • 医学(全般)

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