B-Cell Mitogen Produced by Slime-Forming, Encapsulated Lactococcus lactis ssp. cremoris Isolated from Ropy Sour Milk, Viili

Haruki Kitazawa, Takahiro Yamaguchi, Makoto Miura, Tadao Saito, Takatoshi Itoh

研究成果: Article査読

40 被引用数 (Scopus)

抄録

A substance, active as a B-cell mitogen, was isolated from the slime products produced by Lactococcus lactis ssp. cremoris KVS20. The mitogenic substance was prepared by anion-exchange chromatography and gel filtration chromatography and then purified by proteinase digestion and HPLC. Chemical analysis determined that the mitogenic substance was a phosphopolysaccharide and consisted of rhamnose, glucose, galactose, and phosphorus. The activity of the mitogenic substance was higher than that of the slime products. The optimal concentration for the activity was approximately 120 μg/ml. The mitogenic substance also had substantial mitogenic activity to spleen cells from C3H/HeJ mice, which are resistant to lipopolysaccharide. The findings indicated that a B-cell mitogen different from lipopolysaccharide is produced from L. lactis ssp. cremoris KVS20.

本文言語English
ページ(範囲)1514-1519
ページ数6
ジャーナルJournal of Dairy Science
76
6
DOI
出版ステータスPublished - 1993

ASJC Scopus subject areas

  • 食品科学
  • 動物科学および動物学
  • 遺伝学

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