Autonomous bioactuator driven by chicken cardiomyocytes

Kaori Furuike, Ai Shima, Shotaro Yoshida, Yuya Morimoto, Shoji Takeuchi

研究成果: Conference contribution

抄録

This paper describes a chick embryo cardiomyocyte actuator for investigation of cardiomyocyte contractile properties as alternatives of culture system with rodent cardiomyocytes. Chick embryo cardiomyocytes are more accessible than rat or mouse cardiomyocytes in terms of cost and ethics. We cultured chick embryo cardiomyocytes on parylene sheets and observed that the parylene sheets autonomously flapped with the contractile force of cardiomyocytes. Furthermore, the flap frequency increased in response to the addition of isoproterenol, which promotes contraction of cardiac muscles. This technique would reduce the cost of experiments, and thus be expected to promote the study of contractile properties of cardiomyocytes.

本文言語English
ホスト出版物のタイトル21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
出版社Chemical and Biological Microsystems Society
ページ1441-1442
ページ数2
ISBN(電子版)9780692941836
出版ステータスPublished - 2020
イベント21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
継続期間: 2017 10 222017 10 26

出版物シリーズ

名前21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
CountryUnited States
CitySavannah
Period17/10/2217/10/26

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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引用スタイル