Asymmetric synthesis of pyrimidyl alkanol without adding chiral substances by the addition of diisopropylzinc to pyrimidine-5-carbaldehyde in conjunction with asymmetric autocatalysis

Kenso Soai, Itaru Sato, Takanori Shibata, Soichiro Komiya, Masanobu Hayashi, Yohei Matsueda, Hikaru Imamura, Tadakatsu Hayase, Hiroshi Morioka, Hayami Tabira, Jun Yamamoto, Yasunori Kowata

研究成果: Article査読

192 被引用数 (Scopus)

抄録

Enantiomerically enriched pyrimidyl alkanol with either S or R configuration was obtained stochastically from the reaction between pyrimidine-5-carbaldehyde and diisopropylzinc without adding chiral substances in conjunction with subsequent asymmetric autocatalysis, leading to amplification of the enantiomeric excess.

本文言語English
ページ(範囲)185-188
ページ数4
ジャーナルTetrahedron Asymmetry
14
2
DOI
出版ステータスPublished - 2003 1 17

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

フィンガープリント 「Asymmetric synthesis of pyrimidyl alkanol without adding chiral substances by the addition of diisopropylzinc to pyrimidine-5-carbaldehyde in conjunction with asymmetric autocatalysis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル