抄録
The asymmetric Diels–Alder reaction of α-substituted acrolein proceeds in the presence of the trifluoroacetic acid salt of trifluoromethyl-substituted diarylprolinol silyl ether to afford the exo-isomer with both excellent diastereoselectivity and high enantioselectivity. In the Diels–Alder reaction of a β,β-disubstituted α,β-unsaturated aldehyde, good exo-selectivity and excellent enantioselectivity was obtained when the perchloric acid salt of the bulky triisopropyl silyl ether of trifluoromethyl substituted diarylprolinol was employed as an organocatalyst in the presence of water. In both cases, all-carbon quaternary stereocenters are constructed enantioselectively.
本文言語 | English |
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ページ(範囲) | 15874-15880 |
ページ数 | 7 |
ジャーナル | Chemistry - A European Journal |
巻 | 22 |
号 | 44 |
DOI | |
出版ステータス | Published - 2016 10月 24 |
ASJC Scopus subject areas
- 触媒
- 有機化学