Asymmetric Aldol Reaction of α,α-Disubstituted Acetaldehydes Catalyzed by Diphenylprolinol Silyl Ether for the Construction of Quaternary Stereogenic Centers

Yujiro Hayashi, Hiroki Shomura, Qianqian Xu, Martin James Lear, Itaru Sato

研究成果: Article査読

6 被引用数 (Scopus)

抄録

The asymmetric cross-aldol reaction of α,α-disubstituted acetaldehydes with commercial ethyl glyoxylate polymer was successfully catalyzed by diphenylprolinol silyl ether 3 to generate all-carbon quaternary stereogenic centers with good enantioselectivity. Diphenylprolinol silyl ether is an effective organocatalyst in the asymmetric cross-aldol reaction of α,α-disubstituted acetaldehydes with commercial ethyl glyoxylate polymer to generate all-carbon quaternary stereogenic centers with good enantioselectivity.

本文言語English
ページ(範囲)4316-4319
ページ数4
ジャーナルEuropean Journal of Organic Chemistry
2015
20
DOI
出版ステータスPublished - 2015 7月 1

ASJC Scopus subject areas

  • 物理化学および理論化学
  • 有機化学

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