TY - JOUR
T1 - Astatine-211 imaging by a Compton camera for targeted radiotherapy
AU - Nagao, Yuto
AU - Yamaguchi, Mitsutaka
AU - Watanabe, Shigeki
AU - Ishioka, Noriko S.
AU - Kawachi, Naoki
AU - Watabe, Hiroshi
PY - 2018/9
Y1 - 2018/9
N2 - Astatine-211 is a promising radionuclide for targeted radiotherapy. It is required to image the distribution of targeted radiotherapeutic agents in a patient's body for optimization of treatment strategies. We proposed to image 211At with high-energy photons to overcome some problems in conventional planar or single-photon emission computed tomography imaging. We performed an imaging experiment of a point-like 211At source using a Compton camera, and demonstrated the capability of imaging 211At with the high-energy photons for the first time.
AB - Astatine-211 is a promising radionuclide for targeted radiotherapy. It is required to image the distribution of targeted radiotherapeutic agents in a patient's body for optimization of treatment strategies. We proposed to image 211At with high-energy photons to overcome some problems in conventional planar or single-photon emission computed tomography imaging. We performed an imaging experiment of a point-like 211At source using a Compton camera, and demonstrated the capability of imaging 211At with the high-energy photons for the first time.
KW - Astatine-211
KW - Compton camera
KW - Monte Carlo simulation
KW - Targeted radiotherapy
UR - http://www.scopus.com/inward/record.url?scp=85048468045&partnerID=8YFLogxK
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U2 - 10.1016/j.apradiso.2018.05.022
DO - 10.1016/j.apradiso.2018.05.022
M3 - Article
C2 - 29864741
AN - SCOPUS:85048468045
VL - 139
SP - 238
EP - 243
JO - Applied Radiation and Isotopes
JF - Applied Radiation and Isotopes
SN - 0969-8043
ER -