Associations between prenatal exposure to volatile organic compounds and neurodevelopment in 12-month-old children: The Japan Environment and Children's Study (JECS)

the Japan Environment and Children's Study (JECS) Group

研究成果: Article査読

抄録

In recent years, there has been an increase in the number of problems associated with neurodevelopmental disorders in children, and there has been a growing interest in the relationship between environmental chemicals and children's health. The objective of this study was to examine whether an association exists between occupational or environmental prenatal maternal exposure to volatile organic compounds and the risk of neurodevelopmental disorders in children using Japanese translations of the Ages & Stages Questionnaires, Third Edition (J-ASQ-3). An increase in the risk of neurodevelopmental delay in 12-month-old children associated with maternal exposure to formalin or formaldehyde was identified in terms of problem-solving (odds ratio (OR): 1.76, 95% confidence interval (CI): 0.99–3.12) and personal-social skills (OR: 3.32, 95% CI: 1.46–7.55). It is not clear whether or not this tendency is reversible, and whether it is observed past 12 months of age. Further research and a preventive approach are needed.

本文言語English
論文番号148643
ジャーナルScience of the Total Environment
794
DOI
出版ステータスPublished - 2021 11 10

ASJC Scopus subject areas

  • 環境工学
  • 環境化学
  • 廃棄物管理と処理
  • 汚染

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