Association of rotavirus and human immunodeficiency virus infection in children hospitalized with acute diarrhea, lusaka, zambia

Hitoshi Oshitani, F. C. Kasolo, M. Mpabalwani, N. P. Luo, N. Matsubayasbi, G. H. Bhat, G. H. Bhat, H. Suzuki, Y. Numazaki, A. Zumla, H. L. Du Pont

研究成果: Article査読

21 被引用数 (Scopus)

抄録

In Lusaka, Zambia, rotavirus (RV) and human immunodeficiency virus (HIV) infection commonly coexist; 132 (25%) of 537 consecutively studied infants <5 years old hospitalized with diarrhea were positive for both viral infections. Infants with RV infection were younger than those who were RV-negative (P>.05), and infants with both viruses more frequently experienced dehydration (P <.05). HIV-infected children more often exhibited respiratory symptoms on admission to the study (P <.0001) and were more frequently underweight (P <.0001) than were HIV-negative children, independent of RV infection. The mortality rate was highest in HIV-positive infants (P <.05), and coinfection with RV did not increase the risk of fatality. This study demonstrates that while RV and HIV infections commonly coexist in one region of Africa, RV infection is no more common nor is the illness more severe in HIV-positive infants.

本文言語English
ページ(範囲)897-900
ページ数4
ジャーナルJournal of Infectious Diseases
169
4
DOI
出版ステータスPublished - 1994 4月 1

ASJC Scopus subject areas

  • 免疫アレルギー学
  • 感染症

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