Aspartate-immunoreactive primary sensory neurons in the mouse trigeminal ganglion

H. Ichikawa, S. Matsuo, R. Terayama, T. Yamaai, T. Sugimoto

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Aspartate-immunoreactivity (ir) was examined in the mouse trigeminal ganglion (TG). The ir was detected in 34% of TG neurons and their cell bodies were of various sizes (mean ± S.D. = 1234 ± 543 μm2). A triple immunofluorescence method revealed the co-expression of aspartate with calcitonin gene-related peptide (CGRP) and parvalbumin; 22% and 14% of aspartate-immunoreactive (ir) neurons were also immunoreactive for CGRP and parvalbumin, respectively. The co-expression of aspartate with both CGRP and parvalbumin was very rare in the TG. By retrograde tracing method, half and 66% of TG neurons which innervate the vibrissa and palate, respectively, contained aspartate-ir. The co-expression of aspartate with CGRP was more common among palatal neurons (36%) compared to vibrissal neurons (22%). Aspartate-ir neurons which co-expressed parvalbumin-ir were numerous in the vibrissa (17%) but not in the palate (4%). These findings may suggest that the function of aspartate-containing TG neurons is correlated with their peripheral receptive fields.

本文言語English
ページ(範囲)67-72
ページ数6
ジャーナルBrain research
1082
1
DOI
出版ステータスPublished - 2006 4 12
外部発表はい

ASJC Scopus subject areas

  • 神経科学(全般)
  • 分子生物学
  • 臨床神経学
  • 発生生物学

フィンガープリント

「Aspartate-immunoreactive primary sensory neurons in the mouse trigeminal ganglion」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル