Application of optogenetics in epilepsy research

研究成果: Chapter

抄録

Epilepsy is a disease characterized by seizures arising from paroxysmal and self-limited hypersynchrony of neurons. However, the mechanism by which the normal brain develops epilepsy, which involves a chronic process of structural and morphological changes known as epileptogenesis, is not fully understood. Optogenetics involves the use of genetic engineering and optics to monitor or control nerve cell activity. Compared to classical electrophysiological experiments, the application of optogenetics in epilepsy research has many advantages because it allows selective photic stimulation of cell types and electrical observation without introducing artifacts.

本文言語English
ホスト出版物のタイトルAdvances in Experimental Medicine and Biology
出版社Springer
ページ557-562
ページ数6
DOI
出版ステータスPublished - 2021

出版物シリーズ

名前Advances in Experimental Medicine and Biology
1293
ISSN(印刷版)0065-2598
ISSN(電子版)2214-8019

ASJC Scopus subject areas

  • 生化学、遺伝学、分子生物学(全般)

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