Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing

Ramin Banan Sadeghian, Jiuhui Han, João Ribas, Amir Nasajpour, Margaux Duchamp, Seyed Ali Mousavi Shaegh, Serge Ostrovidov, Sahar Salehi, Mingwei Chen, Ali Khademhosseini

研究成果: Conference contribution

抄録

We employed the large surface-to-volume ratio of nanoporous gold (NPG) to build a set of highly sensitive superoxide electrochemical biosensors. Once functionalized with cytochrome-c (cyt-c) the NPG-based electrodes displayed a superoxide sensitivity of 0.24 nA nM-1 and a low-level of detection of 5 nM towards superoxide. The planar electrodes were then interfaced with HUVEC cells and were able to detect the release of extracellular superoxide upon stimulation with an endogenous superoxide producer. In addition, we studied the superoxide sensing performance of a three-dimensional (3D) macroporous mesh of gold decorated with NPG as a potential ultrasensitive superoxide biosensor.

本文言語English
ホスト出版物のタイトル16th International Conference on Nanotechnology - IEEE NANO 2016
出版社Institute of Electrical and Electronics Engineers Inc.
ページ19-21
ページ数3
ISBN(電子版)9781509039142
DOI
出版ステータスPublished - 2016 11 21
イベント16th IEEE International Conference on Nanotechnology - IEEE NANO 2016 - Sendai, Japan
継続期間: 2016 8 222016 8 25

出版物シリーズ

名前16th International Conference on Nanotechnology - IEEE NANO 2016

Other

Other16th IEEE International Conference on Nanotechnology - IEEE NANO 2016
国/地域Japan
CitySendai
Period16/8/2216/8/25

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 原子分子物理学および光学

フィンガープリント

「Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル