Aplysianin-A, an antibacterial and antineoplastic glycoprotein in the albumen gland of a sea hare, Aplysia kurodai

H. Kamiya, K. Muramoto, M. Yamazaki

    研究成果: Article査読

    55 被引用数 (Scopus)

    抄録

    Aplysianin-A, an antibacterial and antineoplastic factor in the albumen gland of the sea hare Aplysia kurodai, was isolated. It had a molecular weight of approximately 320 kD and consisted of subunits with a molecular weight of 85 kD. It contained 9.8% neutral sugar. Aplysianin A showed 50% inhibition of Bacillus subtilis growth at a concentration of 4 μg protein/ml and 50% lysis of murine MM46 tumor cells at 14 ng protein/ml. A partial identity of antigenic specificity of the purified specimen with an antineoplastic factor from Aplysia eggs was observed in immunodiffusion tests.

    本文言語English
    ページ(範囲)1065-1067
    ページ数3
    ジャーナルExperientia
    42
    9
    DOI
    出版ステータスPublished - 1986 9 1

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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