Anion recognition by urea and thiourea groups: Remarkably simple neutral receptors for dihydrogenphosphate

Seiichi Nishizawa, Philippe Bühlmann, Masatoshi Iwao, Yoshio Umezawa

研究成果: Article査読

212 被引用数 (Scopus)

抄録

A bis-urea and a bis-thiourea host, both derived in only one step from 1,3-bis(aminomethyl)benzene, are shown to bind dihydrogenphosphate selectively over various other anions (H2PO4- > CH3COO- > Cl- > HSO4- > NO3- > ClO4-). The much stronger binding of H2PO4- by the bis-thiourea is rationalized by the stronger H-bond donor strength of the thiourea groups and the binding selectivity is explained in terms of the complex geometry and the basicity of the guest anions. The lack of self-association and the changes in the UV spectrum upon complexation make bis-thiourea hosts a promising new class of neutral receptors for dihydrogenphosphate.

本文言語English
ページ(範囲)6483-6486
ページ数4
ジャーナルTetrahedron Letters
36
36
DOI
出版ステータスPublished - 1995 9月 4
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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