An enzyme logic bioprotonic transducer

Takeo Miyake, Erik E. Josberger, Scott Keene, Yingxin Deng, Marco Rolandi

    研究成果: Article査読

    33 被引用数 (Scopus)

    抄録

    Translating ionic currents into measureable electronic signals is essential for the integration of bioelectronic devices with biological systems. We demonstrate the use of a Pd/PdHx electrode as a bioprotonic transducer that connects H+ currents in solution into an electronic signal. This transducer exploits the reversible formation of PdHx in solution according to PdH虠Pd + H+ + e-, and the dependence of this formation on solution pH and applied potential. We integrate the protonic transducer with glucose dehydrogenase as an enzymatic and gate for glucose and NAD+. PdHx formation and associated electronic current monitors the output drop in pH, thus transducing a biological function into a measurable electronic output.

    本文言語English
    論文番号014906
    ジャーナルAPL Materials
    3
    1
    DOI
    出版ステータスPublished - 2015 1 1

    ASJC Scopus subject areas

    • 材料科学(全般)
    • 工学(全般)

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