An efficient partial reduction of α,β-unsaturated esters using DIBAL-H in flow

Masahito Yoshida, Hiroyuki Otaka, Takayuki Doi

研究成果: Article査読

10 被引用数 (Scopus)

抄録

The partial reduction of α,β-unsaturated esters and benzoate derivatives to form the corresponding aldehydes was achieved using a flow reactor system within 1 s at a high flow rate (18 mL min-1) under cryogenic conditions (-97°C). Commercially available diisobutylaluminium hydride (DIBAL-H) was used as the reductant. The desired enals and benzaldehyde derivatives, except for 4-methoxycinnamate and 4-methoxybenzoate, were formed selectively and redox economically in moderate to high yields.

本文言語English
ページ(範囲)6010-6016
ページ数7
ジャーナルEuropean Journal of Organic Chemistry
2014
27
DOI
出版ステータスPublished - 2014 9

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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