An efficient, facile, and general synthesis of 1H-indazoles by 1,3-dipolar cycloaddition of arynes with diazomethane derivatives

Tienan Jin, Yoshinori Yamamoto

研究成果: Article査読

141 被引用数 (Scopus)

抄録

(Chemical Equation Presented) Take your pick: Both N-unsubstituted and 1-aryl 1H-indazoles are available in good to high yields through the [3+2] cycloaddition of benzynes derived from o-silylaryl triflates with diazomethane derivatives (see scheme). In the presence of KF/[18]crown-6, the N-unsubstituted 1H-indazole is formed, whereas the 1-arylated product is obtained regioselectively with CsF and an excess of the triflate.

本文言語English
ページ(範囲)3323-3325
ページ数3
ジャーナルAngewandte Chemie - International Edition
46
18
DOI
出版ステータスPublished - 2007 6月 29

ASJC Scopus subject areas

  • 触媒
  • 化学 (全般)

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