Ampelopsins E, E, H and cis-ampelopsin E, oligostilbenes from Ampelopsis brevipedunculata var. Hancei roots

Yoshiteru Oshima, Yuji Ueno

研究成果: Article査読

87 被引用数 (Scopus)

抄録

The methanol extract of the roots of Ampelopsis brevipedunculata var. hancei exhibited marked protective activity against carbon tetrachloride and d-galactosamine-induced liver damage in primary cultured rat hepatocytes. The extract was fractionated by monitoring the activity to give active fractions from which four novel oxidative oligostilbenes, ampelopsins D, E, H and cis-ampelopsin E, were isolated in addition to the known compounds, (-)-epicatechin, pallidol, miyabenol C, piceid, cis-piceid and resveratroloside. The structures of the new stilbene derivatives have been established on the basis of spectroscopic evidence and chemical reactions. Among them, ampelopsin E and cis-ampelopsin E showed antihepatotoxic activity.

本文言語English
ページ(範囲)179-182
ページ数4
ジャーナルPhytochemistry
33
1
DOI
出版ステータスPublished - 1993 4月 29

ASJC Scopus subject areas

  • 生化学
  • 分子生物学
  • 植物科学
  • 園芸学

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