Aligning collagen fibers by cyclic mechanical stretch for efficiently muscle cell actuator

Keiji Seki, Masahiro Shimizu, Kota Miyasaka, Toshihiko Ogura, Koh Hosoda

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

Muscle cell actuators are composed of skeletal muscle cells and collagen intercellular matrix. Muscle cells adhere to collagen fibers and contraction along with the direction of collagen fiber. Collagen fibers in a muscle cell actuator transmit contraction force of each muscle cells along longitudinal direction. In order to improve contraction force of muscle cell actuators, it is very important to align collagen fibers. In this study, we aim to achieve alignment of collagen fibers in the actuator. We developed the automatic culture system which apply cyclic stretch to muscle cell actuators. We estimated the structure the actuator by using a scanning electron microscope and fluorescent observation. And we confirmed that cyclic stretch induced alignment of collagen fibers in the muscle cell actuators.

本文言語English
ホスト出版物のタイトル2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016
出版社Institute of Electrical and Electronics Engineers Inc.
ページ1197-1202
ページ数6
ISBN(電子版)9781509043644
DOI
出版ステータスPublished - 2016
イベント2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016 - Qingdao, China
継続期間: 2016 12 32016 12 7

出版物シリーズ

名前2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016

Other

Other2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016
CountryChina
CityQingdao
Period16/12/316/12/7

ASJC Scopus subject areas

  • Hardware and Architecture
  • Artificial Intelligence
  • Control and Systems Engineering

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