Activation of ATP receptor increases the cytosolic Ca2+ concentration in ventral tegmental area neurons of rat brain

Masaru Sorimachi, Kazuhiko Yamagami, Minoru Wakomori

研究成果: Article査読

12 被引用数 (Scopus)

抄録

ATP increased the cytosolic Ca2+ concentration ([Ca]i) in neurons of ventral tegmental area acutely dissociated from rat brain. The ATP response was dependent on external Ca2+ and Na+, and was blocked by voltage-dependent Ca2+ channel blockers. The results suggest that the ATP-induced depolarization increases Ca2+ influx via voltage-gated Ca2+ channels resulting in the increase in [Ca]i.

本文言語English
ページ(範囲)129-133
ページ数5
ジャーナルBrain research
935
1-2
DOI
出版ステータスPublished - 2002 5 10
外部発表はい

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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