Acid-neutralizing activity during amino acid fermentation by Porphyromonas gingivalis, Prevotella intermedia and Fusobacterium nucleatum

研究成果: Article査読

68 被引用数 (Scopus)

抄録

Acid-neutralizing activity during amino acid fermentation by washed cells of Porphyromonas gingivalis, Prevotella intermedia and Fusobacterium nucleatum was studied. When the washed cells of these strains were anaerobically incubated in the presence of aspartylaspartic acid or glutamylglutamic acid for P. gingivalis, aspartic acid for P. intermedia and glutamic acid for F. nucleatum at an initial pH of 5.0 or 5.5, the pH of the incubation mixtures rose toward neutral. F. nucleatum had the highest acid-neutralizing activity, followed by P. intermedia and P. gingivalis. The P. intermedia and F. nucleatum cells were used to measure the amounts of base produced at a fixed pH of 5.0. These cells generated significant amounts of base at pH 5.0 along with the production of organic acids and ammonia from aspartic or glutamic acid. Acid-base balance theoretically calculated from the amounts of consumed substrate and end products implies that the acid-neutralizing activity was derived from the decrease in acidity during the fermentation of amino acid into organic acids and ammonia.

本文言語English
ページ(範囲)109-113
ページ数5
ジャーナルOral Microbiology and Immunology
18
2
DOI
出版ステータスPublished - 2003 4

ASJC Scopus subject areas

  • 微生物学
  • 免疫学
  • 歯科学(全般)
  • 微生物学(医療)

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