Absence of IgG1 response in the cerebrospinal fluid of relapsing neuromyelitis optica

Ichiro Nakashima, K. Fujihara, J. Fujimori, K. Narikawa, T. Misu, Y. Itoyama

研究成果: Article査読

32 被引用数 (Scopus)

抄録

The authors studied immunoglobulin (Ig) G subclasses in the CSF and sera of patients with relapsing neuromyelitis optica (RNMO) and typical multiple sclerosis (MS). Although the total IgG concentrations were elevated in the CSF of patients with RNMO and MS, IgG1% and IgG1 index were significantly elevated only in patients with MS. The absence of the CSF IgG1 responses in the patients with RNMO may suggest less Thl immunity and may also explain the rarity of oligoclonal IgG bands in patients with this disease.

本文言語English
ページ(範囲)144-146
ページ数3
ジャーナルNeurology
62
1
DOI
出版ステータスPublished - 2004 1 13

ASJC Scopus subject areas

  • 臨床神経学

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