A study of the self-assembling morphology in peptide nanorings and nanotubes

Hajime Okamoto, Tsutomu Nakanishi, Yukiko Nagai, Tetsuo Yamada, Hiroshi Miyazaki, Kyozaburo Takeda, Yukio Furukawa, Ikuo Obataya, Hisakazu Mihara, Hiroaki Azehara, Wataru Mizutani, Katsushi Hashimoto, Hiroshi Yamaguchi, Yoshiro Hirayama

研究成果: Conference article査読

1 被引用数 (Scopus)


Peptide nanotubes of cyclo[-(D-Ala-L-Gln)4], cyclo[-(D-Ala-L-Gln)3], cyclo[-(D-Cys-L-Gln)3], and cyclo[-(L-Gln)5] have been synthesized and their morphologies have been studied by scanning probe microscopy. The atomic force microscopy displayed several interesting self-assembling forms of these peptide nanotubes. The three D,L-peptides showed not only the straight tubular forms but also the self-assembled bundles. The number and size of observed nanotubes and their bundles were different among those three and also among employed solvents and substrates. On the contrary, the homo-L-peptide of cyclo[-(L-Gln)5] provided meandering nanotubes, which were caused by the symmetry lowering due to the odd number of amino acids. The meandering characteristics also resulted peculiar super-ring forms of the homo-L-peptide nanotubes. Additionally, the scanning tunneling microscopy was performed and high-resolution images of D,L-peptide nanotubes as well as their bundles were obtained.

ジャーナルMaterials Research Society Symposium Proceedings
出版ステータスPublished - 2004 12 1
イベント2003 MRS Fall Meeting - Boston, MA, United States
継続期間: 2003 12 12003 12 5

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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