A phase II study of an enhanced recovery after surgery protocol in gastric cancer surgery

Norihiko Sugisawa, Masanori Tokunaga, Rie Makuuchi, Yuichiro Miki, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Masanori Terashima

研究成果: Article査読

42 被引用数 (Scopus)

抄録

Background: The enhanced recovery after surgery (ERAS) protocol integrates a number of perioperative interventions and techniques, aiming at decreasing the morbidity rate and the length of postoperative hospital stay after surgery. Although it has become a standard perioperative management for colorectal surgery, the feasibility of the ERAS protocol for gastric surgery remains unclear. Methods: This single-center, prospective phase II study included patients with gastric cancer undergoing curative gastrectomy. The primary end point was the incidence of Clavien–Dindo grade II or higher postoperative complications. The secondary end points were the incidence of anastomotic leakage, the incidence of pneumonia, the proportion of patients starting oral feeding at postoperative day 2, the completion rate of the ERAS protocol, the length of postoperative hospital stay, the readmission rate within 30 days after discharge, and the mortality rate. Results: From September 2013 to September 2014, 121 eligible patients were enrolled in this study. The incidence of postoperative complications was 10.7 % (90 % confidence interval, 6.47–16.54 %). Anastomotic leakage and pneumonia was observed in one and zero patients, respectively. The median length of postoperative hospital stay was 8 days, and the completion rate of the ERAS protocol was 85.1 %. The readmission rate and the mortality rate were 0 %. Conclusions: The ERAS protocol can be safely used in patients undergoing gastric cancer surgery. The superiority of the ERAS protocol over non-ERAS perioperative management should be clarified.

本文言語English
ページ(範囲)961-967
ページ数7
ジャーナルGastric Cancer
19
3
DOI
出版ステータスPublished - 2016 7月 1

ASJC Scopus subject areas

  • 腫瘍学
  • 消化器病学
  • 癌研究

フィンガープリント

「A phase II study of an enhanced recovery after surgery protocol in gastric cancer surgery」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル