A new hexasaccharide chain isolated from bovine colostrum κ-casein taken at the time of parturition

Tadao Saito, Takatoshi Itoh, Susumu Adachi, Tateo Suzuki, Taichi Usui

研究成果: Article査読

22 被引用数 (Scopus)

抄録

The carbohydrate units linked to caseinoglycopeptide from colostrum taken 30 min after parturition were released as reduced oligosaccharides by alkaline borohydride treatment, and separated into four acidic oligosacchariditols (a hexa- (11.0%), penta- (38.5%), tetra- (35.5%) and a trisacchariditol (15.0%)). Structural studies showed that the hexasacchariditol was a new structure and had the chemical structure: NeuNAc-α-2-3-Gal-β-1-3-[NeuNAc-α-2-3-Gal-β-1-4-GlcNAc-β-1-6-]-N-acetylgalactosaminitol(GalNAcItol). The other three oligosacchariditols were shown to be NeuNAc-α-2-3-Gal-β-1-3-[Gal-β-1-4-GlcNac- β-1-6-]-GalNAcItol, NeuNAc-α-2-3-Gal-β-1-3-[NeuNAc-α-2-6-]-GalNAcItol and NeuNAc-α-2-3-Gal-β-1-3- GalNAcItol, which were identical with those found previously in colostrum κ-casein taken 6 h after parturition.

本文言語English
ページ(範囲)309-317
ページ数9
ジャーナルBBA - General Subjects
719
2
DOI
出版ステータスPublished - 1982 11 24

ASJC Scopus subject areas

  • 生物理学
  • 生化学
  • 分子生物学

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